The thing about most spray bottle designs is that there's always that last bit of juice right at the bottom that gets wasted because the straw can't reach it. But with some simple modifications, you can easily make sure it spritzes its way down to that last drop.

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This clip posted by Instructables user DIYHacksAndHowTos shows off a cheap and simple method to make a spray bottle work regardless of which position you hold it in. Be sure to head over to Instructables for a complete parts list and instructions: